Criminal Minds, the CBS television show centered around a team of profilers from the FBI's Behavioral Analysis Unit (BAU), will be airing an episode entitled True Genius this Wednesday, January 18 @ 9:00 ET. The episode's plot is based on the case of the Zodiac. From the preview (below), it appears that the team is chasing somebody who is recreating the Zodiac's crimes.
I've never watched Criminal Minds, but people appear to like the series reasonably well. I'll be making it a point to check it out on Wednesday. If you're interested in the Zodiac, I suspect you'll find the episode worth watching.
Trivia question: What other two work-of-fiction television series used the Zodiac as a basis for an episode?